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Reviewer of the Month (2024)

In 2024, AOL reviewers continue to make outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.

Hereby, we would like to highlight some of our outstanding reviewers, with a brief interview of their thoughts and insights as a reviewer. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

Is more better? Increased doses of high dose methotrexate and addition of rituximab is associated with improved outcomes in a large primary CNS lymphoma cohort

In the last 30 years, the standard treatments for PCNSL at Memorial Sloan Kettering Cancer Center (MKSCC) have evolved. HDMTX-containing chemotherapy regimen (mainly HDMTX dosed at 3.5 g/m2, vincristine, and procarbazine) has been predominantly used as mainstay treatment. Around 2006, rituximab was added to this regimen more routinely. Moreover, the number of HDMTX doses administered has increased in recent years. The purpose of this retrospective analysis of a large newly diagnosed PCNSL patient population was to investigate if shifts in standard treatment practices were associated with improvement in clinical outcomes.

Complete renal and haematological remission in a case of mantle cell lymphoma associated paraneoplastic focal segmental glomerulosclerosis with ibrutinib: a case report and review of literature

A 73-year-old gentleman presented with 2-month history of bilateral pedal oedema with frothy urine. Examination revealed generalized lymphadenopathy with hepatosplenomegaly. Twenty-four-hour urine protein was 11 grams/total volume, suggesting nephrotic syndrome. There were atypical circulating lymphocytes in the blood. Flowcytometry and cytogenetic studies from bone marrow aspirate and histopathology of lymph node biopsy confirmed the diagnosis of MCL. Kidney biopsy revealed FSGS. The patient was treated with ibrutinib 560 mg once daily considering his age and preference for oral therapy. At the end of two years of follow-up the patient is in complete remission for both MCL and FSGS.

Central Nervous System Lymphomas

In the last decade, international cooperation established consolidated therapeutic guidelines and advanced our learning in some peculiar settings, like vitreoretinal lymphoma and neurolymphomatosis. Basic research critically contributed to these achievements, mostly on activated tumor pathways that could represent suitable targets for novel therapies. The efforts of several multidisciplinary experts led to relevant improvement in outcome and quality of life of patients affected by this dismal disease. Many of these internationally recognized experts contributed to summarize the current knowledge, discuss evidence, provide recommendations, and foresee possible scenarios in this special series of Annals of Lymphoma.

Welcome to Annals of Lymphoma

During my formative years, a textbook of hematology would contain a single, rather brief, chapter on lymphomas. Within the pages would be clinical and pathologic descriptions in broad terms relating to a limited number of recognized histologic subtypes. As our knowledge increased, the chapters were separated into Hodgkin and non-Hodgkin, and then the latter into B- and T-cell. Treatment strategies from that period relied heavily on radiation therapy, but eventually active systemic treatment was available, although founded on those derivatives of mustard gas, the alkylating agents, as well as corticosteroids, and a series of other non-specific cytotoxic drugs. Means to assess response were rudimentary and variable, including radiographs, lymphangiograms and ultrasounds. It was totally unclear why some patients with a similar histologic morphology would be cured, whereas others were resistant to similar treatments. In this context, the glacial speed of journal publications was sufficient.

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Review Article

Peripheral T-cell lymphoma in older patients: a narrative review of initial and subsequent treatments and clinical outcomes

Nathan Roberts, Viktoriya Zelikson, Enrica Marchi

Annals of Lymphoma

2024;

(30 October 2024)

PDF Full Text (112) Reporting Checklist Peer Review File COI Form Open Access

Case Report

Anti-TIF1γ antibody positivity without inflammatory myositis leading to expedited diagnosis of synchronous Epstein-Barr virus-positive marginal zone lymphoma and colon cancer: a case report

Ian J. Robertson, Guen M. Hunt, Michael Loncharich, Daniel V. Cordaro, Christin B. DeStefano

Annals of Lymphoma

2024;

(30 July 2024)

PDF Full Text (472) Reporting Checklist Peer Review File COI Form Open Access

Case Report

Chronic lymphocytic leukemia infiltration of a transplanted kidney successfully treated with venetoclax and obinutuzumab: a case report

Sanjog Bastola, Manoj Rai, Nicole Andeen, Shehzad Rehman, Stephen Spurgeon

Annals of Lymphoma

2024;

(30 June 2024)

PDF Full Text (528) Reporting Checklist Peer Review File COI Form Open Access

Original Article

Pediatric Infradiaphragmatic Hodgkin’s lymphoma: a unique identity

Nashwa Ezzeldeen, Emad Moussa, Madiha El Wakeel, Maha Mehesen, Eman Khorshed, Amr Elnashar, Sara Abdelkerim, Mohamed Saad Zaghloul, Asmaa Hamoda

Annals of Lymphoma

2024;

(30 May 2024)

PDF Full Text (380) Data Sharing Statement Peer Review File COI Form Open Access

Case Report

Relapsed mantle cell lymphoma with parenchymal central nervous system involvement successfully treated with chimeric antigen receptor T-cell therapy—a case report

Manoj Rai, Richard T. Maziarz, Bashi Ratterree, Elizabeth S. Bailey, Esmaa Alshalan, Pamela J. St. Clair, Stephen E. Spurgeon

Annals of Lymphoma

2024;

(30 May 2024)

PDF Full Text (572) Reporting Checklist Peer Review File COI Form Open Access

Review Article

The role of pathologic testing in the diagnosis and management of patients with diffuse large B cell lymphoma: a narrative review

Michael Schneider, Daniel Landsburg

Annals of Lymphoma

2024;

(30 May 2024)

PDF Full Text (464) Reporting Checklist Peer Review File COI Form Open Access

Case Report

Complete renal and haematological remission in a case of mantle cell lymphoma associated paraneoplastic focal segmental glomerulosclerosis with ibrutinib: a case report and review of literature

Urmimala Bhattacharjee, Sarthak Wadhera, Arihant Jain, Ritambhra Nada, Sreejesh Sreedharanunni, Man Updesh Singh Sachdeva, Pankaj Malhotra

Annals of Lymphoma

2023;

(30 March 2023)

PDF Full Text (1507) Reporting Checklist COI Form Open Access

Original Article

Is more better? Increased doses of high dose methotrexate and addition of rituximab is associated with improved outcomes in a large primary CNS lymphoma cohort

Prakirthi Yerram, Samantha N. Reiss, Lisa Modelevsky, Lauren Schaff, Anne S. Reiner, Katherine S. Panageas, Christian Grommes

Annals of Lymphoma

2023;

(28 February 2023)

PDF Full Text (1884) Reporting Checklist Data Sharing Statement COI Form Open Access

Review Article

State of the art in the diagnosis, biology and treatment of primary mediastinal B-cell lymphoma: a review

Vincent Camus, Fanny Drieux, Fabrice Jardin

Annals of Lymphoma

2022;

(30 December 2022)

PDF Full Text (5932) COI Form Open Access

Review Article

Older patients with mantle cell lymphoma: initial and subsequent therapies—a narrative review

Sowjanya Vuyyala, Tycel Jovelle Phillips

Annals of Lymphoma

2022;

(30 December 2022)

PDF Full Text (2796) Reporting Checklist COI Form Open Access

Review Article

Clinical geriatric assessment in older patients with lymphoma: a narrative review

Giulia Soverini, Alessandra Tucci

Annals of Lymphoma

2022;

(30 September 2022)

PDF Full Text (2299) Reporting Checklist COI Form Open Access

Review Article

Age is just a number: managing relapsed or refractory diffuse large B-cell lymphoma (DLBCL) in older patients

Danielle S. Wallace, Patrick M. Reagan

Annals of Lymphoma

2022;

(30 September 2022)

PDF Full Text (3662) COI Form Open Access

Review Article

Initial treatment of elderly population with aggressive lymphoma: a narrative review of current evidence and future directions

Behzad Amoozgar, Brad S. Kahl

Annals of Lymphoma

2022;

(30 September 2022)

PDF Full Text (5925) Reporting Checklist COI Form Open Access

Review Article

Transplant and chimeric antigen receptor T-cell therapies in elderly patients with lymphoma, a narrative review

I. Brian Greenwell, Parastoo B. Dahi

Annals of Lymphoma

2022;

(30 September 2022)

PDF Full Text (2478) Reporting Checklist COI Form Open Access

Editorial

Preface: virus-associated lymphomas

Christopher P. Fox, Claire Shannon-Lowe

Annals of Lymphoma

2022;

(30 September 2022)

PDF Full Text (1308) COI Form Open Access

Review Article

Diffuse large B-cell lymphoma among the elderly: a narrative review of current knowledge and future perspectives

Tove Wästerlid, Shannon Murphy, Diego Villa, Tarec C. El-Galaly

Annals of Lymphoma

2022;

(30 June 2022)

PDF Full Text (9094) Reporting Checklist COI Form Open Access

Review Article

Adoptive cellular immunotherapy for Epstein-Barr virus-associated lymphoproliferative disease

Birte Wistinghausen, Hema Dave, Catherine M. Bollard

Annals of Lymphoma

2022;

(30 June 2022)

PDF Full Text (2985) COI Form Open Access

Editorial

The diversity challenges in follicular lymphoma

Mark Roschewski, Carla Casulo

Annals of Lymphoma

2022;

(30 June 2022)

PDF Full Text (1612) COI Form Open Access

Case Report

The gamma delta lymphomas: an Australian multi-centre case series

Sean Harrop, Pietro Di Ciaccio, Nicole Wong Doo, Tara Cochrane, Belinda A. Campbell, Nada Hamad, Michael Dickinson, Carrie Van Der Weyden, Henry Miles Prince

Annals of Lymphoma

2022;

(30 March 2022)

PDF Full Text (5014) Reporting Checklist COI Form Open Access

Case Report

Complete response of relapsed adult T-cell lymphoma leukemia to a Bcl-2 inhibitor: a case report

Alessandra Petrillo, Maher Albitar, Tatyana Feldman

Annals of Lymphoma

2022;

(30 March 2022)

PDF Full Text (2526) Reporting Checklist COI Form Open Access

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Review Article

Narrative review of chronic active EBV infection—advances in clinical management

Akihisa Sawada, Masami Inoue

Published online: 30 March 2021

PDF Full Text (31538) Reporting Checklist COI Form Open Access

Review Article

Aggressive B-cell lymphomas—from morphology to molecular pathogenesis

Bo-Jung Chen, Falko Fend, Elias Campo, Leticia Quintanilla-Martinez

Published online: 08 January 2019

PDF Full Text (26239) COI Form Open Access

Review Article

Mantle cell lymphoma pathology update in the 2016 WHO classification

Luis Veloza, Inmaculada Ribera-Cortada, Elias Campo

Published online: 18 March 2019

PDF Full Text (21679) COI Form Open Access

Review Article

Prognostic factors and risk of transformation in marginal zone lymphoma

Juan Pablo Alderuccio, Izidore S. Lossos

Published online: 30 September 2020

PDF Full Text (17376) COI Form Open Access

Review Article

New drugs for the management of relapsed or refractory diffuse large B-cell lymphoma

Clémentine Sarkozy, Laurie H. Sehn

Published online: 27 November 2019

PDF Full Text (16659) COI Form Open Access

Review Article

Radiation therapy of extranodal marginal zone lymphomas

Letizia Deantonio, Chelsea C. Pinnix, Richard Tsang

Published online: 30 December 2020

PDF Full Text (13529) COI Form Open Access

Review Article

Diffuse large B-cell lymphoma—who should we FISH?

Deborah M. Stephens, Sonali M. Smith

Published online: 28 November 2018

PDF Full Text (12896) COI Form Open Access

Review Article

Risk stratification and management algorithms for patients with diffuse large B-cell lymphoma and CNS involvement

Teresa Calimeri, Paolo Lopedote, Andrés J. M. Ferreri

Published online: 18 July 2019

PDF Full Text (11244) COI Form Open Access

Review Article

Epidemiology of marginal zone lymphoma

James R. Cerhan, Thomas M. Habermann

Published online: 30 March 2021

PDF Full Text (10106) COI Form Open Access

Review Article

Unmet needs in histological transformation of follicular lymphoma: a clinical and biological review

Miguel Alcoceba, Sara Alonso-Álvarez, María García-Álvarez, Alejandro Martín, M. Dolores Caballero

Published online: 14 December 2017

PDF Full Text (10071) COI Form Open Access

Review Article

Recent advances in the first-line treatment of mantle cell lymphoma

Morgane Cheminant, Martin Dreyling, Olivier Hermine

Published online: 31 March 2020

PDF Full Text (9886) COI Form Open Access

Review Article

Primary diffuse large B-cell lymphoma of the central nervous system: molecular and biological features of neoplastic cells

Francesco Bertoni, Manuel Montesinos-Rongen

Published online: 30 March 2022

PDF Full Text (9757) COI Form Open Access

Review Article

Responses and response evaluation of immune checkpoint inhibitors in lymphoma

Theodora Anagnostou, Stephen M. Ansell

Published online: 10 November 2017

PDF Full Text (9435) COI Form Open Access

Review Article

The contribution of ebv to the pathogenesis of classical hodgkin lymphoma

Katerina Vrzalikova, Matthew Pugh, Lucia Mundo, Paul Murray

Published online: 30 September 2021

PDF Full Text (9282) COI Form Open Access

Review Article

Management of relapsed and refractory mantle cell lymphoma: a review of current evidence and future directions for research

David A. Bond, Kristie A. Blum, Kami Maddocks

Published online: 09 November 2017

PDF Full Text (9262) COI Form Open Access

Review Article

Treatment of elderly patients with primary CNS lymphoma

Nicolas Martinez-Calle, Lisa K. Isbell, Kate Cwynarski, Elisabeth Schorb

Published online: 30 March 2021

PDF Full Text (9182) COI Form Open Access

Review Article

Diffuse large B-cell lymphoma among the elderly: a narrative review of current knowledge and future perspectives

Tove Wästerlid, Shannon Murphy, Diego Villa, Tarec C. El-Galaly

Published online: 30 June 2022

PDF Full Text (9094) Reporting Checklist COI Form Open Access

Review Article

Relapsed and refractory primary CNS lymphoma: treatment approaches in routine practice

Prakash Ambady, Nancy D. Doolittle, Christopher P. Fox

Published online: 30 September 2021

PDF Full Text (8759) COI Form Open Access

Review Article

Disparities in lymphoma on the basis of race, gender, HIV status, and sexual orientation

Melody Becnel, Christopher R. Flowers, Loretta J. Nastoupil

Published online: 17 November 2017

PDF Full Text (8548) COI Form Open Access

Review Article

Pathology of extranodal marginal zone lymphoma at different anatomic sites

Andrew Wotherspoon

Published online: 30 December 2020

PDF Full Text (7953) COI Form Open Access

Full Most Read article list >>

Review Article

Disparities in lymphoma on the basis of race, gender, HIV status, and sexual orientation

Melody Becnel, Christopher R. Flowers, Loretta J. Nastoupil

Review Article

Hodgkin lymphoma and PD-1 blockade: an unfinished story

Reid Merryman, Philippe Armand

Review Article

Responses and response evaluation of immune checkpoint inhibitors in lymphoma

Theodora Anagnostou, Stephen M. Ansell

Review Article

Unmet needs in histological transformation of follicular lymphoma: a clinical and biological review

Miguel Alcoceba, Sara Alonso-Álvarez, María García-Álvarez, Alejandro Martín, M. Dolores Caballero

Journal Highlight more

Annals of Lymphoma, is an open access, international, peer-reviewed electronic journal, and openly distributed worldwide. It publishes articles that describe advances in basic and translational science, and clinical findings relating to human lymphoma. Specific areas of interest include, but are not limited to, epidemiology, biology, genetics, immunology, diagnosis, treatment, and measures of assessment of response.